Metabolic Syndrome X

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Already in the 20s of the twentieth century it was known that obesity may be associated with hypertension, a change in the lipid composition of the blood, impaired glucose tolerance and type II diabetes.


However, the first one in 1988 these states joined in a single cause-related "Syndrome X" was G.Reaven.


After analyzing the data of numerous studies, he came to the conclusion that the basis of hyperinsulinemia, glucose intolerance, changes in the lipid composition of the blood and high blood pressure may lie decrease in insulin sensitivity.


In 1989, M. Kaplan emphasizes obesity in the abdominal area. According to him, the four "deadly quartet" includes:


obesity


+ Type II diabetes mellitus


+ Arterial hypertension


+ Hypertriglyceridemia.


It is this combination significantly increases mortality rates from cardiovascular diseases.